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My Medicare 2019

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Active substance(s): RAMIPRIL

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PACKAGE LEAFLET: INFORMATION FOR THE USER
Ramipril 1.25 mg Capsules
Ramipril 2.5 mg Capsules
Ramipril 5 mg Capsules
Ramipril 10 mg Capsules
(Ramipril)
Read all of this leaflet carefully before you start taking this medicine because it contains
important information for you.
 Keep this leaflet. You may need to read it again.
 If you have any further questions, ask your doctor, pharmacist or nurse.
 This medicine has been prescribed for you only. Do not pass it on to others. It may harm them
even if their symptoms are the same as yours.
 If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible
side effects not listed in this leaflet.
In this leaflet:
1. What Ramipril is and what it is used for
2. What you need to know before you take Ramipril
3. How to take Ramipril
4. Possible side effects
5. How to store Ramipril
6. Contents of the pack and other information
1.
WHAT RAMIPRIL IS AND WHAT IT IS USED FOR
Ramipril contains a medicine called Ramipril. This belongs to a group of medicines called ACE
inhibitors (Angiotensin Converting Enzyme Inhibitors).
Ramipril works by:
 Decreasing your body’s production of substances that could raise your blood pressure
 Making your blood vessels relax and widen
 Making it easier for your heart to pump blood around your body.
Ramipril can be used:
 To treat high blood pressure (hypertension)
 To reduce the risk of you having a heart attack or stroke
 To reduce the risk or delay the worsening of kidney problems (whether or not you have
diabetes)
 To treat your heart when it cannot pump enough blood to the rest of your body (heart failure)
 As treatment following heart attack (myocardial infarction) complicated with heart failure.
2.
WHAT YOU NEED TO KNOW BEFORE YOU TAKE RAMIPRIL
Do not take Ramipril:
 If you are allergic (hypersensitive) to ramipril, any other ACE inhibitor medicine or any of the
ingredients of Ramipril listed in section 6.
Signs of an allergic reaction may include a rash, swallowing or breathing problems, swelling
of your lips, face, throat or tongue
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 If you have ever had a serious allergic reaction called “angioedema”. The signs include itching,
hives (urticaria), red marks on the hands, feet and throat, swelling of the throat and tongue,
swelling around the eyes and lips, difficulty breathing and swallowing
 If you are having dialysis or any other type of blood filtration. Depending on the machine that is
used, Ramipril may not be suitable for you
 If you have kidney problems where the blood supply to your kidney is reduced (renal artery
stenosis)
 If you have diabetes or impaired kidney function and you are treated with a blood pressure
lowering medicine containing aliskiren.
 During the last 6 months of pregnancy (see section below on “Pregnancy and breast-feeding”)
 If your blood pressure is abnormally low or unstable. Your doctor will need to make this
assessment.
Do not take Ramipril if any of the above apply to you. If you are not sure, talk to your doctor before
taking Ramipril.
Warnings and precautions
Talk to your doctor, pharmacist or nurse before taking Ramipril:
 If you have heart, liver or kidney problems
 If you have lost a lot of body salts or fluids (through being sick (vomiting), having diarrhoea,
sweating more than usual, being on a low salt diet, taking diuretics (water tablets) for a long
time or having had dialysis)
 If you are going to have treatment to reduce your allergy to bee or wasp stings (desensitization)
 If you are going to receive an anaesthetic. This may be given for an operation or any dental
work. You may need to stop your Ramipril treatment one day beforehand; ask your doctor for
advice
 If you have high amounts of potassium in your blood (shown in blood test results)
 If you have a collagen vascular disease such as scleroderma or systemic lupus erythematosus
 If you are taking any of the following medicines, the risk of angioedema (rapid swelling under
the skin in area such as the throat) is increased:
- sirolimus, everolimus and other medicines belonging to the class of mTOR inhibitors (used to
avoid rejection of transplanted organs)
 If you are taking any of the following medicines used to treat high blood pressure:
- an angiotensin II receptor blocker (ARBs) (also known as sartans - for example valsartan,
telmisartan, irbesartan), in particular if you have diabetes-related kidney problems.
- aliskiren
Your doctor may check your kidney function, blood pressure, and the amount of electrolytes (e.g.
potassium) in your blood at regular intervals.
See also information under the heading “Do not take Ramipril”.
You must tell your doctor if you think that you are (or might become) pregnant. Ramipril is not
recommended in the first 3 months of pregnancy and may cause serious harm to your baby after 3
months of pregnancy, see section “Pregnancy and breast-feeding”.
Children and adolescents
Ramipril is not recommended for use in children and adolescents below 18 years of age because safety
and efficacy of Ramipril in children has not yet been established.
If any of the above apply to you (or you are not sure), talk to your doctor before taking Ramipril.
Other medicines and Ramipril
Page 3 of 9
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other
medicines, including medicines obtained without a prescription (including herbal medicines).
This is because Ramipril can affect the way some other medicines work. Also some medicines can
affect the way Ramipril works. Your doctor may need to change your dose and/or to take other
precautions.
Please tell your doctor if you are taking any of the following medicines. They can make Ramipril work
less well:
 Medicines used to relieve pain and inflammation (e.g. Non-Steroidal Anti-Inflammatory Drugs
(NSAIDs) such as ibuprofen or indomethacin and aspirin)
 Medicines used for the treatment of low blood pressure, shock, cardiac failure, asthma or
allergies such as ephedrine, noradrenaline or adrenaline. Your doctor will need to check your
blood pressure.
Please tell your doctor if you are taking any of the following medicines. They can increase the chance
of getting side effects if you take them with Ramipril:
 Medicines used to relieve pain and inflammation (e.g. Non-Steroidal Anti-Inflammatory Drugs
(NSAIDs) such as ibuprofen or indometacin and aspirin)
 Medicines for cancer (chemotherapy)
 Medicines which are most often used to avoid rejection of transplanted organs (ciclosporin,
sirolimus, everolimus and other medicines belonging to the class of mTOR inhibitors). See
section “Warnings and precautions”.
 Diuretics (water tablets) such as furosemide
 Medicines which can increase the amount of potassium

My Medical 2.5